Clinical and Laboratory Standards Institute CLSI. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically; Approved Standard - Tenth Edition. CLSI document M07-A10, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA, 2015. Various pharmacokinetic parameters of the local anesthetics can be significantly altered by the presence of hepatic or renal disease, addition of epinephrine, factors affecting urinary pH, renal blood flow, the route of drug administration, and the age of the patient. If you are using other inhalers at the same time, wait at least 1 minute between the use of each medication. asne.info pantoprazole
Standard Ampicillin powder should provide the following range of MIC values noted in Table 2. For the diffusion technique using the 10 mcg ampicillin disk, the criteria in Table 2 should be achieved. Repeat these steps for your other eye if so directed. Apply the medication usually 1 to 3 times daily or as directed by your doctor. At the back of your throat, two masses of tissue called act as filters, trapping germs that could otherwise enter your airways and cause infection. They also produce antibodies to fight infection. But sometimes the themselves become infected.
Ask your health care provider any questions you may have about how to use enoxaparin. Remember that the total combined duration of use of Ketorolac tromethamine tablets and IV or IM dosing of Ketorolac tromethamine is not to exceed 5 days in adults. Ketorolac tromethamine tablets are not indicated for use in pediatric patients. Craig WA, Gerber AU "Worldwide experience with bacampicillin administered twice a day. Contact your health care provider if you have any questions.
Do not use this medication if you are allergic to ampicillin or to any other penicillin antibiotic, such as amoxicillin Amoxil carbenicillin Geocillin dicloxacillin Dycill, Dynapen oxacillin Bactocill penicillin Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids and others. Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA, 2012. Ferrieri P, Gewitz MH, Gerber MA et al and the Committee on Rheumatic Fever et al. Unique features of infective endocarditis in childhood. Circulation. Learn which of your inhalers you should use every day and which you should use if your breathing suddenly worsens quick-relief drugs.
Infants 3 months of age and older and children weighing up to 40 kg 88 lbs. Susceptibility to ampicillin of Staphylococcus spp. This effect may also occur with UNASYN. Infections of the gastrointestinal tract - Shigella, S. typhosa and other Salmonella, E. coli, P. mirabilis, and enterococci. Treatment of endocarditis caused by susceptible staphylococci, streptococci, E. coli, P. mirabilis, or Salmonella. The presence of other medical problems may affect the use of medicines in this class. Depending upon the route of administration, local anesthetics are distributed to some extent to all body tissues, with high concentrations found in highly perfused organs such as the liver, lungs, heart, and brain. Concurrent administration of vasopressor drugs and of ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular accidents. Penicillin G usually preferred for N. meningitidis meningitis and penicillin-susceptible S. pneumoniae meningitis. 5 For H. influenzae meningitis, cefotaxime, ceftriaxone, or, alternatively, ampicillin in conjunction with chloramphenicol is recommended; ampicillin should not be used alone see Ampicillin-resistant Haemophilus influenzae under Cautions. The number of tablets or teaspoonfuls of suspension that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking a penicillin. No dosage adjustments except those related to renal impairment. See Renal Impairment under Dosage and Administration. What should I avoid while taking ampicillin Principen? Neurologic effects following other procedures or routes of administration may include persistent anesthesia, paresthesia, weakness, paralysis, all of which may have slow, incomplete, or no recovery. Duration of therapy depends on type and severity of infection and should be determined by clinical and bacteriologic response of the patient. Mycophenolate: Penicillins may decrease serum concentrations of the active metabolites of Mycophenolate. This effect appears to be the result of impaired enterohepatic recirculation.
Store enoxaparin at room temperature, between 59 and 77 degrees F 15 and 25 degrees C. Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F 15 and 30 degrees C is permitted. Keep enoxaparin out of the reach of children and away from pets. Hypersensitivity reactions have included urticarial rash, erythema multiforme, exfoliative dermatitis, serum sickness-like reactions, edema, hypotension, fever, eosinophilia, dyspnea, interstitial nephritis, Henoch-Schonlein purpura, focal glomerulonephritis, Stevens-Johnson syndrome, bullous pemphigoid, hypersensitivity myocarditis, toxic epidermal necrolysis, and fixed drug eruptions. GU procedures is no longer recommended by the AHA. Consider only in patients with the highest risk of adverse outcome from endocarditis eg, prosthetic heart valve, previous endocarditis, some categories of congenital heart disease, cardiac valvulopathy in cardiac transplant patients who have an established GI or GU enterococcal infection or for those already receiving antibiotic therapy to prevent a wound infection or sepsis associated with a GI or GU procedure in which enterococcal coverage is desired Wilson 2007. Some forms of enoxaparin contain benzyl alcohol. Do not use medicine with benzyl alcohol in NEWBORNS or INFANTS. It may cause serious and sometimes fatal side effects. If you have questions, check with your doctor or pharmacist. These solutions are not for spinal anesthesia. Therefore, elderly people may be more sensitive to this drug. Some penicillin derivatives may accelerate the degradation of aminoglycosides in vitro, leading to a potential underestimation of aminoglycoside serum concentration. Marcaine is contraindicated in patients with a known hypersensitivity to it or to any local anesthetic agent of the amide-type or to other components of Marcaine solutions. This medication has been prescribed for your current condition only. Throw away the unused portion after treatment is completed. Do not use it later for another infection. A different medication may be necessary in that case. Ampicillin can make birth control pills less effective, which may result in pregnancy. Before taking ampicillin, tell your doctor if you use birth control pills. Use this medication regularly to get the most benefit from it. This medication works best if used at evenly spaced intervals. To help you remember, use it at the same times each day. Do not increase your dose, use this medication more often, or stop using it without first consulting your doctor. In most cases, your dentist can treat the cause of bad breath. If your dentist determines that your mouth is healthy and the odor is not of oral origin, you may be referred to your family doctor or to a specialist to determine the odor source and treatment plan. AUC administered after gestation Day 17, caused dystocia and higher pup mortality in rats. Treatment of gastroenteritis caused by susceptible Salmonella. Singh N, Yu VL, Mieles LA, Wagener MM "Beta-lactam antibiotic-induced leukopenia in severe hepatic dysfunction: risk factors and implications for dosing in patients with liver disease. This is given by injection, usually into a muscle as directed by your doctor. When you start treatment for TB, it is usually given once a day or as directed by your doctor. anastrozole
Respiratory side effects have included laryngeal stridor. How often you receive injections and the length of your treatment will depend on the type of infection you have and your response to treatment. Overdose symptoms may include confusion, behavior changes, a severe skin rash, urinating less than usual, or seizure black-out or convulsions. Box 1968, Danbury, CT 06813-1968; phone 203 744-0100; web site www. Units injected into a muscle once a day. UNASYN to individuals with normal renal function. Ask your doctor before you change your diet or the dose of your diabetes medicine. Clinical studies, as well as postmarketing observations, have shown that Ketorolac tromethamine can reduce the natriuretic effect of furosemide and thiazides in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis. During concomitant therapy with NSAIDs, the patient should be observed closely for signs of renal failure see WARNINGS, as well as to assure diuretic efficacy. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your with you, and share the list with your doctor and pharmacist. HACEK organisms, native or prosthetic valve off-label use: 2 g every 4 hours for 4 weeks native valve or 6 weeks prosthetic valve. This information should not be used to decide whether or not to take enoxaparin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about enoxaparin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to enoxaparin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using enoxaparin. Penicillins may cause false test results with some urine sugar tests. Check with your doctor before changing your diet or the dosage of your diabetes medicine. Do not shorten dosing interval of 4 to 6 hours. Most strains of enterococci. The onset of action following dental injections is usually 2 to 10 minutes and anesthesia may last two or three times longer than lidocaine and mepivacaine for dental use, in many patients up to 7 hours.
Most useful for epidural block in abdominal operations requiring complete muscle relaxation, and for retrobulbar anesthesia. Not for obstetrical anesthesia. Tilt your head back, look upward, and gently pull down the lower eyelid to make a pouch. How Does What You Eat Affect Breath? IV route recommended for human or animal bite wounds. Since this drug does not provide coverage for MRSA, an additional agent should be considered for severe bite wounds. Has been used for perioperative prophylaxis in patients undergoing vaginal hysterectomy or cesarean section. Cephalosporins cefazolin, cefotetan, cefoxitin usually drugs of choice for perioperative prophylaxis in patients undergoing obstetric and gynecologic surgery. All patients, irrespective of age and weight: Larger doses may be required for severe or chronic infections. Although ampicillin is resistant to degradation by gastric acid, it should be administered at least one half-hour before or two hours after meals for maximal absorption. Except for the single dose regimen for gonorrhea referred to above, therapy should be continued for a minimum of 48 to 72 hours after the patient becomes asymptomatic or evidence that bacterial eradication has been obtained. Solutions with or without epinephrine. Adverse events have not been observed in animal reproduction studies. Ampicillin crosses the placenta, providing detectable concentrations in the cord serum and amniotic fluid Bolognese 1968; Fisher 1967; MacAulay 1966. Maternal use of ampicillin has generally not resulted in an increased risk of birth defects Aselton 1985; Czeizel 2001b; Heinonen 1977; Jick 1981; Puhó 2007. Ampicillin is recommended for use in pregnant women for the management of preterm premature rupture of membranes PPROM and for the prevention of early-onset group B streptococcal GBS disease in newborns. purchase now generic anafranil online
Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins PBPs which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes autolysins and murein hydrolases while cell wall assembly is arrested. Diarrhea; mild pain, irritation, swelling, redness, bleeding, or bruising at the injection site; nausea. When Ketorolac tromethamine is administered with aspirin, its protein binding is reduced, although the clearance of free Ketorolac tromethamine is not altered. The clinical significance of this interaction is not known; however, as with other NSAIDs, concomitant administration of Ketorolac tromethamine and aspirin is not generally recommended because of the potential of increased adverse effects. Chloroquine: May decrease the serum concentration of Ampicillin. Management: Chloroquine prescribing information recommends separating administration of ampicillin and chloroquine by at least 2 hours to minimize any potential negative impact of chloroquine on ampicillin bioavailability. Solutions of Marcaine may be autoclaved if they do not contain epinephrine. Solutions are clear and colorless. Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This may not be a complete list of all interactions that may occur. Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into muscle. Standards Institute, 950 West Valley Road. Inform your doctor if your condition persists or worsens. Known hypersensitivity to any penicillin. The peak analgesic effect of Ketorolac tromethamine occurs within 2 to 3 hours and is not statistically significantly different over the recommended dosage range of Ketorolac tromethamine. The greatest difference between large and small doses of Ketorolac tromethamine is in the duration of analgesia.
Glossitis, stomatitis, black "hairy" tongue, nausea, vomiting, enterocolitis, pseudomembranous colitis, and diarrhea. These reactions are usually associated with oral dosage forms. Shake the bottle well before each dose. R-enantiomeric forms, with the S-form having analgesic activity. The pH of dilute solutions remains the same. Respiratory tract infections: Treatment of respiratory tract infections caused by S. pneumoniae, Staphylococcus aureus penicillinase and nonpenicillinase producing H. influenzae, and group A beta-hemolytic streptococci. Units, injected into a vein or muscle every four to six hours. What should I discuss with my healthcare provider before taking ampicillin Principen? Store at room temperature away from moisture. not store in the bathroom. Keep new inhalers in the sealed pouch until you are ready to use them. The should be discarded when the dose indicator shows "0", when the inhaler becomes locked, or 45 days after removing the inhaler from the sealed pouch, whichever comes first. Keep all away from children and pets. The condition can occur occasionally or recur frequently. Use in Head and Neck Area: Small doses of local anesthetics injected into the head and neck area, including retrobulbar, dental, and stellate ganglion blocks, may produce adverse reactions similar to systemic toxicity seen with unintentional intravascular injections of larger doses. The injection procedures require the utmost care. Adults: 1000 mg three times a day every eight hours for fourteen days, along with the other medicine, lansoprazole, as directed by your doctor. Parenteral route used for treatment of moderately severe or severe infections. 2 Oral route should not be used for initial treatment of severe, life-threatening infections, but may be used as follow-up after parenteral ampicillin. Gastrointestinal side effects have included diarrhea 5% to 20% nausea, vomiting, anorexia, gastritis, generalized abdominal cramps, oral candidiasis, black hairy tongue, mouth or tongue soreness, glossitis, stomatitis, enterocolitis, and pseudomembranous colitis. Rare cases of pancreatitis have occurred. Penicillins have been used in the elderly and have not been shown to cause different side effects or problems in older people than they do in younger adults. Should superinfection occur, appropriate measures should be taken. Patients with who also have should be given additional appropriate parenteral penicillin treatment. Treatment with ampicillin does not preclude the need for surgical procedures, particularly in staphylococcal infections. florinef canada overnight delivery
Use of this product is restricted to a suitable work area, such as a laminar flow hood. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. CDAD. Hypertoxin producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. Wilson WR, Karchmer AW, Dajani AS et al and the Committee on Rheumatic Fever et al. Antibiotic treatment of adults with infective endocarditis due to streptococci, enterococci, staphylococci, and HACEK microorganisms. JAMA. Make certain your health care professional knows if you are on a low-sodium low-salt diet. Some of these medicines contain enough sodium to cause problems in some people. Gram-positive and gram-negative bacteria that produce β-lactamases, including β-lactamase-producing S. aureus and E. faecalis, are resistant. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.
Injection of repeated doses of local anesthetics may cause significant increases in plasma levels with each repeated dose due to slow accumulation of the drug or its metabolites, or to slow metabolic degradation. Tolerance to elevated blood levels varies with the status of the patient. Debilitated, elderly patients and acutely ill patients should be given reduced doses commensurate with their age and physical status. Local anesthetics should also be used with caution in patients with hypotension or heartblock. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. This product should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. Solutions which are discolored or which contain particulate matter should not be administered. Practice good oral hygiene. Brush twice a day with to remove food debris and plaque. Brush teeth after you eat keep a at work or school to brush after lunch. Don't forget to brush the tongue, too. Replace your every 2 to 3 months or after an illness. Use floss or an interdental cleaner to remove food particles and plaque between teeth once a day. Rinse with an antibacterial mouthwash twice a day. Dentures should be removed at night and cleaned thoroughly before being placed in your mouth the next morning. Sodium Chloride Injection, USP only. Lactobacillus and Estriol: Antibiotics may diminish the therapeutic effect of Lactobacillus and Estriol. Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug NSAID that exhibits analgesic activity in animal models. The mechanism of action of Ketorolac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. The biological activity of Ketorolac tromethamine is associated with the S-form. Ketorolac tromethamine possesses no sedative or anxiolytic properties. Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. Marcaine with epinephrine. Injections should be made slowly and with frequent aspirations. Until further experience is gained, Marcaine in dentistry is not recommended for pediatric patients younger than 12 years. Listeria infections occurring during pregnancy, granulomatosis infantiseptica, sepsis, endocarditis, meningitis, and foodborne infections. 4 5 9 9 See Meningitis and Other CNS Infections under Uses. Moderate-risk patients: 2 g within 30 minutes prior to procedure Dajani 1997. Food and Drug Administration. arava
This may be taken with or without food. However, is best absorbed when taken on an empty 1 hour before or 2 hours after meals. If this occurs, patients should contact their physician as soon as possible. The extent of placental transfer is also determined by the degree of ionization and lipid solubility of the drug. Lipid soluble, nonionized drugs readily enter the fetal blood from the maternal circulation. Hepatic toxicity is usually reversible; however, deaths have been reported. While studies have demonstrated the susceptibility of most strains of the following organisms, clinical efficacy for infections other than those included in the section has not been documented. The in vitro binding of warfarin to plasma proteins is only slightly reduced by Ketorolac tromethamine 99. This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using ampicillin. An initial 2-g dose at time of labor or rupture of membranes followed by 1 g every 4 hours until delivery. For the best effect, use this antibiotic at evenly spaced times. To help you remember, use this medication at the same times every day. Tablets should be chewed or crushed before they are swallowed. There are several different kinds of penicillins. Each is used to treat different kinds of infections. One kind of penicillin usually may not be used in place of another. In addition, penicillins are used to treat bacterial infections in many different parts of the body. They are sometimes given with other antibacterial medicines antibiotics. Some of the penicillins may also be used for other problems as determined by your doctor. However, none of the penicillins will work for colds, flu, or other virus infections.
Tell your doctor or dentist that you take enoxaparin before you receive any medical or dental care, emergency care, or surgery. What Health Problems Are Associated With Bad Breath? Readministration may be needed to ensure adequate serum and tissue drug levels. Reproduction studies have been performed in laboratory animals at doses several times the human dose and have revealed no evidence of adverse effects due to Ampicillin. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Some strengths of the amoxicillin chewable tablets contain aspartame, which is changed by the body to phenylalanine, a substance that is harmful to patients with phenylketonuria. If your symptoms do not improve or if they become worse, check with your doctor. Dolovich J, Ruhno J, Sauder DN, Ahlstedt S, Hargreave FE "Isolated late cutaneous skin test response to ampicillin: a distinct entity. NSAIDs, including Ketorolac tromethamine, can cause serious skin adverse events such as exfoliative dermatitis, Stevens-Johnson syndrome SJS and toxic epidermal necrolysis TEN which can be fatal. These serious events may occur without warning. Patients should be informed about the signs and symptoms of serious skin manifestations and use of the drug should be discontinued at the first appearance of skin rash, mucosal lesions, or any other sign of hypersensitivity. buy diflucan tablets online visa
MRHD on a BSA basis. UNASYN or other products containing ampicillin. Like other β-lactam antibiotics, antibacterial activity results from inhibition of bacterial cell wall synthesis. The incidence and degree of toxicity depend upon the procedure performed, the type, and amount of drug used, and the technique of drug administration. Adverse reactions in the parturient, fetus, and neonate involve alterations of the central nervous system, peripheral vascular tone, and cardiac function. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Ampicillin is excreted in trace amounts in human milk. Therefore, caution should be exercised when Ampicillin-class antibiotics are administered to a nursing woman. Ampicillin Capsules, USP for oral administration provide ampicillin trihydrate equivalent to 250 mg and 500 mg ampicillin. Ampicillin Capsules also contain magnesium stearate. This procedure uses paper disks impregnated with 10 mcg ampicillin to test the susceptibility of bacteria to ampicillin. UNASYN may result in increased and prolonged blood levels of ampicillin and sulbactam. Spectrum of activity includes many gram-positive and -negative aerobes and some anaerobes. Add a total of 70 mL to the 100 mL package and 139 mL to the 200 mL package. This will provide 100 mL and 200 mL of suspension, respectively. Each 5 mL teaspoonful will contain ampicillin trihydrate equivalent to 250 mg ampicillin. Hemic and Lymphatic Systems: anemia, thrombocytopenia, thrombocytopenic purpura, eosinophilia, leukopenia, and agranulocytosis have been reported during therapy with penicillins. These reactions are usually reversible on discontinuation of therapy and are believed to be hypersensitivity phenomena. All medicines may cause side effects, but many people have no, or minor, side effects. Penicillins except bacampicillin tablets, amoxicillin, penicillin V, pivampicillin, and pivmecillinam are best taken with a full glass 8 ounces of water on an empty stomach either 1 hour before or 2 hours after meals unless otherwise directed by your doctor. Some strengths of the chewable tablets of amoxicillin contain aspartame, which is changed by the body to phenylalanine, a substance that is harmful to patients with phenylketonuria. Refer to adult dosing.
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Transient increases in liver function tests and chronic cholestasis have rarely been associated with ampicillin. Acute pancreatitis has been reported and confirmed by rechallenge with ampicillin in a patient in whom there was no other obvious cause of pancreatitis. Sterile isotonic solutions containing sodium chloride. Do not use after the expiration date on the label. The medicine may not work properly after that date. If you have any questions about this, check with your pharmacist. Lanthanum: May decrease the serum concentration of Ampicillin. Management: Administer oral ampicillin at least two hours before or after lanthanum.
Allergic: Allergic-type reactions are rare and may occur as a result of sensitivity to the local anesthetic or to other formulation ingredients, such as the antimicrobial preservative methylparaben contained in multiple-dose vials or sulfites in epinephrine-containing solutions. These reactions are characterized by signs such as urticaria, pruritus, erythema, angioneurotic edema including laryngeal edema tachycardia, sneezing, nausea, vomiting, dizziness, syncope, excessive sweating, elevated temperature, and possibly, anaphylactoid-like symptomatology including severe hypotension. Cross sensitivity among members of the amide-type local anesthetic group has been reported. The usefulness of screening for sensitivity has not been definitely established.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Patients should be informed of the following information before initiating therapy with an NSAID and periodically during the course of ongoing therapy. Patients should also be encouraged to read the NSAID Medication Guide that accompanies each prescription dispensed. Some babies may seem to have normal hearing, but they develop a problem processing sounds. This is called auditory or auditory dyssynchrony. Therapy should always be initiated with IV or IM dosing of Ketorolac tromethamine and Ketorolac Tromethamine Tablets USP are to be used only as continuation treatment, if necessary.
The supine position is dangerous in pregnant women at term because of aortocaval compression by the gravid uterus. Therefore during treatment of systemic toxicity, maternal hypotension or fetal bradycardia following regional block, the parturient should be maintained in the left lateral decubitus position if possible, or manual displacement of the uterus off the great vessels be accomplished. It is extremely important to avoid aortocaval compression by the gravid uterus during administration of regional block to parturients. To do this, the patient must be maintained in the left lateral decubitus position or a blanket roll or sandbag may be placed beneath the right hip and gravid uterus displaced to the left.